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315,316 In a mouse asthma model, transgenic overexpression of Trx significantly reduced MIF expression in the airway epithelial cells and reduced the number of MIF-positive inflammatory cells in the lung parenchyma

While MTX primarily suppresses inflammation by increasing the release of adenosine (a potent natural anti-inflammatory molecule), biologic drugs might directly target and neutralize specific inflammatory proteins like TNF-alpha

Although the neuroprotective effects of UA have been demonstrated in both in vitro and in vivo models, the mechanisms by which UA protects neurons from oxidative stress remain unclear

Concurrently, the conserved structural domains of AsGST proteins were predicted with the NCBI-CDD tool