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Contributions of brain insulin resistance and deficiency in amyloid-related neurodegeneration in Alzheimers disease

Among them, caspase-3 is closely related to apoptosis and is activated by both intrinsic and extrinsic pathways, making it a focus for cancer therapy (Chung et al., 2018)

Neurotoxicology 90, 102111

Fisetin protects PC12 cells from tunicamycin-mediated cell death via reactive oxygen species scavenging and modulation of Nrf2-driven gene expression, SIRT1 and MAPK signaling in PC12 cells