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IGF1R up-regulation exerts a dual radio-protective effect

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The results, expressed in the form of perfusion ratio of ischemic to non-ischemic limb, showed that GSDMD -/- mice group exhibited a lower blood flow perfusion recovery compared to WT mice group with significant differences at the 7th, 14th, and 21st day post-HLI (Fig

The application of most ferroptosis-targeting agents in retinal diseases is still in the preclinical stage of new drug development, and there are no clinical trials yet