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10.1016/j.neulet.2021.136283 14 ChenC.ZhaiE.LiuY.QianY.ZhaoR.MaY.et al (2023)

Rice-Evans et al., 1996)

When the storage capacity is exceeded, accumulated cholesterol crystallizes, leading to hepatocyte apoptosis and the release of cholesterol-crystal-laden lipid droplets ( Figure 2D ) ( In contrast, SAMs accumulate in fibrotic regions and exhibit a pro-fibrogenic transcriptomic profile ( Figure 2E )