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Pennig (JBJSA, 2012) performed a very similar study , randomising into three groups - Hyaluronan, corticosteroids and a placebo

Changes in cell surface charge and transmembrane potential accompanying neoplastic transformation of rat kidney cells

The honest position is this: there is no head-to-head human bioavailability trial telling you which route is superior for this specific molecule, so the best route is not a settled question