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In mammalian cells, six peroxiredoxins isoforms expressed and localized to various cellular compartments function as a peroxidase and contain an active site cysteine that can be oxidized by H 2 O 2 (Rhee et al., 2012)

Accumulation of manganese in rat brain following intranasal administration

These evolutionary studies reveal that fewer clones of cancer cells from the primary tumor site can form metastases in distant organs compared to TDLNs, which might be attributed to the different selective pressures and microenvironments in these organs, such as the varying metabolites in distant organs (161, 162)

For comparisons of 3 groups, one-way Anova was used