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Moreover, other studies have shown that the effect of betaine supplementation in the diet on liver steatosis in mice is related to an increase in AMP-activated protein kinase activation in the liver (Reference Song, Deaciuc and Zhou35)

DOI: 10.1111/j.1399-3011.1981.tb01993.x

2 Macules are slightly more common in women than in men and tend to appear in adults between the ages of 30 and 50, although they can develop at any age