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Reduced glutathione is generally preferred for its stronger antioxidant activity, but it is also more prone to oxidation when exposed to air and light

315 Astrocytes in AxD show profound alterations in morphology and function, with evidence of abnormal glutamate clearance, substantial cell stress in the form of upregulated expression of heat shock protein, MAPK pathways, JNK and p38 kinases, as well as increased autophagy and proteasomal activity

For cation-exchange chromatography, phosphate buffer (10 to 50 mM) between pH 5.0 and 7.5 should be tried first