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Without it, cells struggle to maintain redox balance, leading to metabolic inefficiencies

Mitochondrial damage and apoptosis One of the critical pathways through which CT drugs exert their side effect toxicity is by causing mitochondrial damage and inducing apoptosis, which is distinct from ferroptosis (Li et al

The fractions containing eluted protein were loaded onto a 5 ml HiTrap Heparin HP affinity column (Cytiva) pre-equilibrated in H buffer containing 150 mM NaCl and eluted with an increasing salt gradient to 1 M NaCl

As such, they have been quantified in models of inflammatory disease, like atherosclerosis, to identify relationships between disease progression and oxidative damage ( Reference Lakshmi, Padmaja and Kuppusamy 54 )